A postdoctoral position is available at the University of Newcastle, UK

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There is increasing evidence suggesting a causal role for cell senescence and senescence-like signaling in mammalian ageing. DNA damage response and increased ROS production in senescent cells are connected by positive feedback loops involving p38MAPK and TGF. Frequencies of senescent cells increase in many tissues of ageing mice, and this is rescued by dietary restriction. The researcher will assess the role of cell senescence and senescence-like signaling in mouse models of accelerated agei...

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