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Gast
The Ntziachristos laboratory studies the mechanistic aspects of oncogenesis with an emphasis on transcriptional and epigenetic regulation of acute leukemia. We study how oncogenes interact with each other and with epigenetic modulators to influence gene expression programs as well as how their function is related to tri-dimensional (3D) structure of the nucleus and other biological aspects of cancer cells, like metabolism. Recent studies by our group focus on how active deubiquitination controls…
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